Pricey Prostate Cancer drug's makers targeted by Congress

Lawmakers again are targeting the pharmaceutical industry over sky-high prescription drug prices, a hot issue this year in Washington and on the campaign trail that's been dragging down stock prices of many drugmakers.
Shares of Medivation tumbled Tuesday after a group of lawmakers started a campaign to potentially lower the price of a drug for advanced prostate cancer, Xtandi.
The drug is jointly marketed in the U.S. by Japanese drugmaker Astellas Pharma and its partner, Medivation Inc., which is based in San Francisco. Astellas sells Xtandi outside the U.S.
In a letter to the heads of the Department of Health and Human Services and the National Institutes of Health, Reps. Lloyd Doggett and Peter Welch and Sen. Bernie Sanders urged the agencies to step in to cut prices for Xtandi, saying it costs four times more in the U.S. than in some other developed countries.
They are asking for public hearings on the drug, which they say was developed at the University of California, Los Angeles, through taxpayer-supported research grants. The lawmakers want the NIH to consider overriding Xtandi's patent, which guarantees Medivation and Astellas exclusive sales for a decade or more. Overriding the patent would allow for Xtandi's price to be reduced.
"Under current law, NIH can take this step if federal funds supported a drug's development and the company is selling it at an unreasonably high price," the lawmakers said in a statement.
In the U.S., Xtandi has an average list price of more than $129,000 per year, though insurers negotiate significant discounts. Patients generally take if for several months. Xtandi is sold in Japan and Sweden for $39,000, and in Canada for $30,000, according to the statement.