Wednesday, July 1, 2015

Spainish scientists find new biomarkers for the prevention of Colon Cancer

Scientists from the Instituto de Investigación Biomédica (IBI) [Institute of Biomedical Research], in Galicia (Spain), have made progress in the identification of new biomarkers for improving prevention of colorectal cancer. In Spain, colorectal tumours are the most common malignant form and constitute the second most frequent cause of death from cancer, after lung cancer. It is one of the cancers against which preventive strategies could be most effective, as generally it develops from a previous benign polyp called adenoma, which can be detected and removed prior to evolution to cancer. Worldwide, colon cancer is the third most common type of cancer and the second in terms of deaths caused, although the survival rate varies very much from country to country. In the USA the survival rate is 62%, whereas in Europe it is only 43%.
Within the overall structure of the project, the Galician group, led by Professor Javier Rodríguez Berrocal, is undertaking a sub-study of protein biomarkers in the serum of healthy individuals. This research will assess the efficacy of certain proteins in the early detection of colon cancer and adenomas. In a first phase, work begun in 2009 will be completed to identify potentially effective markers. In a second phase, the validity of these markers will be confirmed in a group of individuals who participate in screening programs for this type of cancer.

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