Thursday, July 16, 2015

Immunotherapy vaccine to transform Cancer Treatment

Driven by its proprietary platform, ImPACT, Heat is developing multiple vaccines for a number of different cancers. Vaccines have transformed polio, tetanus, chicken pox and measles from being deadly diseases, to merely something we take a shot for today. Cancer could become the next disease to be virtually eliminated by a vaccine.
ImPACT genetically modifies human cancer cells to pump out antigens (biological agents that target the immune system) and proteins to create an immune response and attack a specific cancer. Not like competitor's drugs that take days, if not weeks, to work, Heat's therapy takes only a few minutes. Then the vaccine lives at the site of the tumor, continuously targeting and destroying the cancer.
Heat's vaccine platform is easy to make, stays on the shelf until needed, and can be given to anybody, regardless of their blood type or DNA makeup, which is unique in the cancer immunotherapy market.
ImPACT will direct its drugs to kill cancer cells faster with immunotherapy that activates, stimulates, and strengthens a patient's immune system to attack a deadly disease with no known cure. Besides lung cancer, Heat targets bladder cancer with HS-410, now in Phase II at 16 US clinical sites (including Johns Hopkins, known for its extensive urological work) to potentially enter a market estimated at $300 million in the next two years. Expected completion of enrollment for the bladder cancer trial is the third quarter of next year.

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