Thursday, April 28, 2016

Drugmakers place big bets on Cancer Medicines

Drugmakers are placing multibillion-dollar bets on new medicines they expect will command premium prices and generate big sales.
France’s Sanofi SA said Thursday it made an unsolicited, $9.3 billion offer to purchase San Francisco-based Medivation Inc., which sells a prostate-cancer drug that recently drew criticism from members of Congress over its price tag. It is Sanofi’s latest effort to expand its cancer-treatment business as sales of its older drugs decline. Medivation’s board was scheduled to meet Thursday to review the offer.
 AbbVie Inc. of North Chicago, Ill., agreed to pay $5.8 billion to acquire a privately held cancer-drug developer, Stemcentrx Inc., of South San Francisco, Calif., continuing AbbVie’s aggressive push to build an oncology business. Stemcentrx’s investors include a venture-capital fund founded by Peter Thiel, a co-founder of PayPal Holdings Inc. and an early investor in Facebook Inc. The flurry of deal activity surrounding cancer drugs comes as politicians, doctors and health-insurance companies blast the pharmaceutical industry for its pricing, particularly for new cancer treatments with monthly costs that commonly exceed $10,000 a month patient.
Medivation’s Xtandi, a prostate-cancer drug introduced in 2012 that costs about $129,000 a patient annually in the U.S. and had sales of $1.9 billion last year. In March, several members of Congress sent a letter to the U.S. Department of Health and Human Services, saying the drug’s “unreasonably high cost” was limiting patient access.
Bristol-Myers Squibb Co. said Thursday that sales of its new immune-stimulating drug Opdivo jumped to $704 million for the first quarter of 2016, from $40 million a year earlier. The drug, launched in late 2014, costs per $12,500 a month patient, on average.

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