A committee of national experts, led by a Cleveland Clinic
researcher, has established first-of-its-kind guidelines to promote more
accurate and individualized cancer predictions, guiding more precise
treatment and leading to improved patient survival rates and outcomes.
These new guidelines are changing the traditional approach of cancer
staging methods for cancer treatment. The new risk calculators, which
will complement the existing staging system, will enable physicians to
more accurately and precisely determine the best treatment for
individual patients.
The American Joint Committee on Cancer (AJCC), which is responsible
for periodically evaluating and updating the cancer stages, has
acknowledged that cancer stages are imperfect, and it is committed to
enhancing the system with more prognostic, statistically based risk
calculators in 2016.
"This represents a new paradigm shift for the future of cancer treatments,"
The formulas must predict overall survival or death from a particular
type of cancer and have to pass all 16 criteria. "Our checklist should
open the door to a wave of statistical prediction models that get used
clinically across many different cancers," said Kattan, a pioneer in the
development of cancer risk calculators called nomograms. "It could
potentially be applied outside cancer as well, anywhere statistical
prediction models are being considered for widespread usage."
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