Cancer researchers from the University of Glasgow and Royal Philips
Cancer researchers have identified a gene which could help doctors to
predict the aggressiveness of prostate cancer in patients. Prostate cancer is the fourth most common cause of cancer death
in the UK, claiming the lives of approximately 11,000 men each year1.
It is also the most common cancer in men in the UK, accounting for a
quarter of all new cases of cancer in males, around 42,000 each year in
total.
They examined 1,475 patient samples to learn more about the
expression of a particular gene, known as PDE4D7. They found that the
gene provided a valuable insight into the aggressiveness of prostate
cancer, and the likely recurrence of the disease after treatment.
Professor George Baillie, of the University of Glasgow, said:
"Prostate cancer, like any other cancer, is a genetic disease which is
driven by the activation of cancer-causing oncogenes and at the same
time by inactivation of tumor-suppressor genes.
The gene we examined acts as a more effective biomarker to predict
the aggressiveness of patients' prostate cancer than any others which
have been used before.
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