AML is an aggressive form of cancer that kills 90% of people over 65 who are diagnosed. Drugs that operate on stem cells are the most effective in treating the disease.
“The stem cell is really the cell that drives the disease,” said Professor Paul Spagnuolo, a researcher from the University of Waterloo responsible for the study, in a statement about the paper. “The stem cell is largely responsible for the disease developing and it’s the reason why so many patients with leukemia relapse.”
While the drug is still years away from being approved for market use, Spagnuolo is already preparing it for a Phase I clinical trial.
"Not
only does avocatin B eliminate the source of AML, but its targeted,
selective effects make it less toxic to the body, too."
"The
stem cells are largely responsible for AML and it is the reason why so
many patients with leukemia relapse," said researcher Paul Spagnuolo,
professor at University of Waterloo in Canada.
"We have performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed," Spagnuolo, who discovered the compound, said.
"We have performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed," Spagnuolo, who discovered the compound, said.
"The
stem cells are largely responsible for AML and it is the reason why so
many patients with leukemia relapse," said researcher Paul Spagnuolo,
professor at University of Waterloo in Canada.
"We have performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed," Spagnuolo, who discovered the compound, said.
"We have performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed," Spagnuolo, who discovered the compound, said.
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